Scientists speed up bone growth
Researchers at the University of California in San Diego have reported that they have developed a new technique which allows them to speed up bone growth by using nanotubes and stem cells. These results are of huge importance that could improve recovery in patients who undergo orthopedic surgery.
What did the scientists do? They used a “bionanotechnology” technique of placing mesenchymal stem cells on top of very thin titanium oxide nanotubes in order to control the conversion paths, called differentiation, into osteoblasts or bone building cells. Mesenchymal stem cells, which are different from embryonic stem cells, can be extracted and directly supplied from a patient’s own bone marrow.
“If you break your knee or leg from skiing, for example, an orthopedic surgeon will implant a titanium rod, and you will be on crutches for about three months,” said Sungho Jin, one of the researchers.
“But we have discovered through our research that if the surgeon uses titanium oxide nanotubes with stem cells, the bone healing could be accelerated and a patient may be able to walk in one month instead of being on crunches for three months,” adds Jin.
This is the first research of its kind — combining stem cells with titanium oxide nanotube implants. The scientists’ plan for the near future is to communicate with orthopedic surgeons in order to translate this breakthrough research to clinical application.
The details are published in Proceedings of the National Academy of Sciences.
Source: ucsd.edu

