Communication signal for tissue development discovered
Rensselaer Polytechnic Institute (PRI) and it’s researchers have discovered a communication signal between cells which play a big role in adhesion and detachment. This research has discovered new information about how cells and tissues determine when to let go from surface during their growth. The research was conducted on fruit fly – a model that helps better understanding of MMPs (metalloproteinases). Fruit fly has two metalloproteinases, compared to 22 which are found in both human and mice. This research showed that one of the two MMPs in fruit fly chops off a piece of a protein which is called Ninjurin A located at cell’s surface. The piece that falls off then sends a signal to other cells that it’s time to detach from their surface. This all should help in tissue development.
