Crystallize nanoparticles — cure cancer
The Chinese Academy of Sciences Institute of Processing Engineering has been home to a research performed by a team of scientists, led by Prof. MA Guanghui. They developed a one-pot approach to couple the crystallization of CaCO3 nanoparticles and the in-situ symmetry-breaking assembly of these crystallites into hollow spherical shells under the templating effect of a soluble starch.
Their further functional studies using HP-a as an anticancer drug carrier demonstrated its advantages for localizing drug release by the pH value-sensitive structure and enhancing cytotoxicity by increasing cellular uptake, perinuclear accumulation, and nuclear entry.
The research was funded by the National Natural Science Foundation of China, CAS, and Ministry of Science and Technology.
Source: cas.cn
