New treatment for bladder cancer
Scientists from University of Columbia have developed a new method for bladder cancer treatment. The experiments were done on mice — researchers “copied” almost all aspects of human bladder cancer. The new method disrupts a signaling pathway, known as mTOR, which blocks tumor growth. Scientists have found that a drug called rapamycin inhibits mTOR and slows down tumor growth in mice.
One of the researchers, Dr. Abate-Shen said: “We believe that this new mouse model of human bladder cancer will be invaluable to the field of bladder cancer research. Already it has provided a relevant preclinical model for therapeutic investigations and a strong rationale for targeting the mTOR signaling pathway in patients with invasive bladder cancer.”
“This new mouse model is enormously important for the study of bladder cancer,” said Daniel P. Petrylak, anohter member of the researching crew.
The details are published in Genes & Development.
